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Cancer BiologyPLOS ONE
Peer-reviewed journal article

Third-generation dual-source computed tomography of the abdomen: comparison of radiation dose and image quality of 80kVp and 80/150kVp with tin filter

S. J. Choi, S. H. Park, S. J. Ahn, S. H. Park, J. W. Choi, S. Y. Pak, Y. S. Shim, Y. M. Jeong, B. Kim

Abstract

ObjectiveTo compare the radiation dose, objective and subjective image quality, and diagnostic performances of 80 kVp and 80/150 kVp with tin filter (80/Sn150 kVp) computed tomography (CT) in oncology patients. MethodsOne hundred forty-five consecutive oncology patients who underwent third-generation dual-source dual-energy CT of the abdomen for evaluation of malignant visceral, peritoneal, extraperitoneal, and bone tumor were retrospectively recruited. Two radiologists independently reviewed each observation in 80 kVp CT and 80/Sn150 kVp CT. Modified line-density profile of the tumor and contrast-to-noise ratio (CNR) were measured. Diagnostic confidence, lesion conspicuity, and subjective image quality were calculated and compared between image sets. ResultsModified line-density profile analysis revealed higher attenuation differences between the tumor and the normal tissue in 80 kVp CT than in 80/Sn150 kVp CT (127 vs. 107, P = 0.05). The 80 kVp CT showed increased CNR in the liver (8.0 vs. 7.6) and the aorta (18.9 vs. 16.3) than the 80/Sn150 kVp CT. The 80 kVp CT yielded higher enhancement of organs (4.9 {+/-} 0.2 vs. 4.7 {+/-} 0.4, P < 0.001) and lesion conspicuity (4.9 {+/-} 0.3 vs. 4.8 {+/-} 0.5, P = 0.035) than the 80/Sn150 kVp CT; overall image quality and confidence index were comparable. The effective dose reduced by 45.2% with 80 kVp CT (2.3 mSv {+/-} 0.9) compared to 80/Sn150 kVp CT (4.1 mSv {+/-} 1.5). ConclusionsThe 80 kVp CT performed similar or better than 80/Sn150 kVp CT for abdominal tumor evaluation with 45.2% radiation dose reduction in oncology patients.

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02 /Specification & Classification

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