Author

J. W. Guarnieri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Angelin· 2 shared T. Lie· 2 shared A. Borczuk· 1 shared A. Chadburn· 1 shared A. Olali· 1 shared B. Agan· 1 shared C. L. Dalgard· 1 shared C. Lim· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. Angelin

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Author profile →

2 papers

Recent·Most cited

Lethal COVID-19 Associates With RAAS-Induced Inflammation For Multiple Organ Damage Including Mediastinal Lymph Nodes

J. W. Guarnieri, M. Topper, K. Beigel, J. A. Haltoom, A. Chadburn, J. Frere, J. An, H. Cope, A. Borczuk, S. Sinha, C. Lim, J. Kim, J. Park, C. Meydan, J. Foox, , K Clark

This study identifies non-canonical genes linked to RAAS overactivation in lethal COVID-19, causing multi-organ damage and mediastinal lymph node dysfunction.

bioRxiv · Oct 8, 2023 · PreprintImmunology

SARS-CoV-2 Viroporins Activate The NLRP3-Inflammasome Via The Mitochondrial Permeability Transition Pore

J. W. Guarnieri, A. Angelin, D. G. Murdoch, P. Portluri, T. Lie, D. C. Wallace

This study shows SARS-CoV-2 viroporins E and Orf3a increase mitochondrial calcium and reactive oxygen species, which activate the NLRP3 inflammasome via the mitochondrial permeability transition pore.

bioRxiv · Feb 19, 2022 · PreprintImmunology