Author

C. Meydan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2 Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 7 Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Assay:bulk RNA-seq· 4 Research Focus:differential expression· 4 Approach:statistical model· 4 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2

Frequent Co-Authors

J. Foox· 4 shared A. Chadburn· 2 shared A. M. Melnick· 2 shared A. Melnick· 2 shared C. E. Mason· 2 shared C. Mason· 2 shared C. Mozsary· 2 shared D. Butler· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersImmunology

J. Foox

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Lethal COVID-19 Associates With RAAS-Induced Inflammation For Multiple Organ Damage Including Mediastinal Lymph Nodes

J. W. Guarnieri, M. Topper, K. Beigel, J. A. Haltoom, A. Chadburn, J. Frere, J. An, H. Cope, A. Borczuk, S. Sinha, C. Lim, J. Kim, J. Park, C. Meydan, J. Foox, , K Clark

This study identifies non-canonical genes linked to RAAS overactivation in lethal COVID-19, causing multi-organ damage and mediastinal lymph node dysfunction.

bioRxiv · Oct 8, 2023 · PreprintImmunology

Cooperative super-enhancer inactivation caused by heterozygous loss of CREBBP and KMT2D skews B cell fate decisions and yields T cell-depleted lymphomas

J. Li, C. R. Chin, H.-Y. Ying, C. Meydan, M. R. Teater, M. Xia, P. Farinha, K. Takata, C.-S. Chu, M. A. Rivas, A. Chadburn, C. Steidl, D. W. Scott, R. G. Roeder, C. E. Mason, , A. M. Melnick

This study shows that combined loss of CREBBP and KMT2D disrupts super-enhancer function in B cells, leading to immune evasion and T cell depletion in lymphomas.

bioRxiv · Feb 13, 2023Cancer Biology

A wipe-based stool collection and preservation kit for microbiome community profiling

H. Hua, C. Meydan, E. Afshin, L. Lili, C. D'Adamo, J. Dudley, N. Price, B. Zhang, C. Mason

This paper introduces and validates a DESS wipe-based method for stool collection and preservation, showing high accuracy and diversity maintenance compared to freezing and commercial kits.

bioRxiv · Dec 3, 2021Microbiology

Systemic Tissue and Cellular Disruption from SARS-CoV-2 Infection revealed in COVID-19 Autopsies and Spatial Omics Tissue Maps

J. Park, J. Foox, T. Hether, D. Danko, S. Warren, Y. Kim, J. Reeves, D. J. Butler, C. Mozsary, J. Rosiene, A. Shaiber, E. Afshinnekoo, M. MacKay, Y. Bram, V. Chandar, , Schwar

This study identifies systemic tissue and cellular disruption from SARS-CoV-2 infection using autopsy and spatial omics data, showing tissue-specific damage and transcriptional changes.

bioRxiv · Mar 8, 2021 · PreprintMicrobiology

Cell-free DNA (cfDNA) and exosome profiling from a year-long humanspaceflight reveals circulating biomarkers

D. Bezdan, K. Grigorev, C. Meydan, F. Pelissier Vatter, M. Ciofi, V. Rao, K. Nakahira, P. Burnham, E. Afshinnekoo, C. Westover, D. Butler, C. Moszary, M. MacKay, J. Foox, T. Mishra, , C. Mason

This study profiles cfDNA and exosomes from an astronaut during a year-long spaceflight, identifying increased cf-mtDNA and exosomal brain-derived peptides as potential biomarkers of spaceflight-related stress.

bioRxiv · Nov 8, 2020Cell Biology

Transcriptional response modules characterise IL-1β and IL-6 activity in COVID-19

L. C. K. Bell, C. Meydan, J. Kim, J. Foox, D. Butler, C. E. Mason, S. D. Shapira, M. Noursadeghi, G. Pollara

The paper identifies IL-1β and IL-6 transcriptional response modules in COVID-19 and finds they reflect cytokine bioactivity without correlating with disease severity.

bioRxiv · Jul 22, 2020Immunology

Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma

R. Ordonez, M. Kulis, N. Russinol, V. Chapaprieta, R. Beekman, C. Meydan, M. Duran-Ferrer, N. Verdaguer-Dot, G. Clot, R. Vilarrasa-Blasi, L. Garate, E. Miranda, A. Carrasco, T. Ezponda, A. Vilas-Zornoza, , J. I. Martin-Subero

The paper identifies aberrant chromatin activation as a common mechanism driving the malignant phenotype in multiple myeloma.

bioRxiv · Aug 20, 2019Cancer Biology