Prolonged exposure to lung-derived cytokines is associated with inflammatory activation of microglia in patients with COVID-19
R. A. Grant, T. A. Poor, L. Sichizya, E. Diaz, J. I. Bailey, S. Soni, K. J. Senkow, X. G. Perez-Leonor, H. Abdala-Valencia, Z. Lu, H. K. Donnelly, R. M. Tighe, J. W. Lomasney, R. G. Wunderink, B. D. Singer, , The NU SCRIPT Investigators
The paper shows that prolonged exposure to lung-derived cytokines in COVID-19 patients activates microglia, and corticosteroids reduce this inflammatory response.
bioRxiv · Jul 28, 2023Immunology