Author

E. Diaz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2 Animal Behavior & Cognition· 1 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 6 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:statistical model· 2

Frequent Co-Authors

A. V. Misharin· 2 shared H. Abdala-Valencia· 2 shared J. I. Bailey· 2 shared K. J. Senkow· 2 shared R. A. Grant· 2 shared R. M. Tighe· 2 shared Z. LuiD· 2 shared A. Bharat· 1 shared

Activity by Year

2021-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

A. V. Misharin

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Identification of a Musashi2 translocation as a novel oncogene in myeloid leukemia

K. Spinler, M. Hamilton, J. Bajaj, Y. Shima, E. Diaz, M. Kritzik, T. Reya

This study identifies MSI2-HOXA9 as a novel oncogenic translocation driving blast crisis in myeloid leukemia, showing increased aggressiveness and mitochondrial activation.

bioRxiv · Dec 29, 2023Cancer Biology

Domestic dogs in indigenous Amazonian communities: key players in Leptospira cycling and transmission?

D. A. Guzman, E. Diaz, C. Saenz, H. Alvarez, R. Cueva, G. Zapata-Rios, B. Prado-Vivar, M. Falconi, T. Pearson, V. Barragan

This study finds high prevalence of Leptospira antibodies and DNA in domestic dogs from Amazonian communities, suggesting their role in Leptospira cycling and transmission.

bioRxiv · Sep 19, 2023 · PreprintMicrobiology

Comparative metabolomics and microbiome analysis of Ethanol vs. OMNImet/gene GUT fecal stabilization

H. Isokaanta, L. Pinto da Silva, N. Karu, T. Kallonen, A. K. Aatsinki, T. Hankemeier, L. Schimmel, E. Diaz, T. Hyotylainen, P. C. Dorrestein, R. Knight, M. Oresic, R. K. Daouk, A. M. Dickens, S. Lamichhane

This study compares the stability of fecal metabolome and microbiome using 95% ethanol and commercial kits under different storage conditions, finding comparable results to flash freezing.

bioRxiv · Aug 29, 2023 · PreprintBiochemistry

Expansion of profibrotic monocyte-derived alveolar macrophages in patients with persistent respiratory symptoms and radiographic abnormalities after COVID-19

J. I. Bailey, C. H. Puritz, K. J. Senkow, N. S. Markov, E. Diaz, E. Jonasson, Z. Yu, S. Swaminathan, Z. Lu, S. Fenske, R. A. Grant, H. Abdala-Valencia, R. J. Mylvaganam, J. Miller, R. I. Cumming, , M. A. Sala

The paper identifies profibrotic monocyte-derived alveolar macrophages and neutrophil recruitment as drivers of lung fibrosis in patients with persistent respiratory symptoms and radiographic abnormalities after COVID-19.

bioRxiv · Jul 30, 2023Immunology

Prolonged exposure to lung-derived cytokines is associated with inflammatory activation of microglia in patients with COVID-19

R. A. Grant, T. A. Poor, L. Sichizya, E. Diaz, J. I. Bailey, S. Soni, K. J. Senkow, X. G. Perez-Leonor, H. Abdala-Valencia, Z. Lu, H. K. Donnelly, R. M. Tighe, J. W. Lomasney, R. G. Wunderink, B. D. Singer, , The NU SCRIPT Investigators

The paper shows that prolonged exposure to lung-derived cytokines in COVID-19 patients activates microglia, and corticosteroids reduce this inflammatory response.

bioRxiv · Jul 28, 2023Immunology

Gasdermin B over-expression arbitrates HER2-targeted therapy resistance by inducing protective autophagy

M. Gamez-Chiachio, A. Molina-Crespo, C. Ramos-Nebot, J. Martinez-Val, L. Martinez, K. Gassner, F. J. Llobet, C. Gonzalo-Consuegra, M. Cordani, C. Bernado-Morales, E. Diaz, A. Rojo-Sebastian, J. C. Trivino, L. Sanchez, R. Rodriguez-Barrueco, , G. Moreno-Bueno

This study identifies GSDMB over-expression as a driver of HER2-targeted therapy resistance through autophagy induction and shows that combining lapatinib with chloroquine enhances therapeutic efficacy in GSDMB-positive tumors.

Journal of Experimental & Clinical Cancer Research · Sep 26, 2022Peer-reviewedCancer Biology

Surprise-induced enhancements in the associability of Pavlovian cues facilitate learning across behavior systems

I. Marquez, G. Loewinger, J. P. Vargas, J. C. Lopez, E. Diaz, G. R. Esber

The paper demonstrates that surprising outcome violations in one behavior system enhance learning in another, supporting the idea that associability enhancements are not system-specific.

bioRxiv · Jun 14, 2021Animal Behavior & Cognition