J. W. Tay

Asymmetric survival in single-cell lineages of cyanobacteria in response to photodamage

The paper uses time-lapse fluorescence microscopy and computational analysis to study photodamage asymmetry in cyanobacterial single-cell lineages, revealing an asymmetric response and a new subcellular structure called a photoendosome.

CyAn: A MATLAB toolbox for image and data analysis of cyanobacteria

CyAn is a MATLAB toolbox that automates the analysis of fluorescence microscopy images of cyanobacteria, enabling tracking of cell growth and differentiation.

Single Cell Analysis Reveals Multiple Requirements for Zinc in the Mammalian Cell Cycle

This study shows that zinc deficiency causes cell cycle arrest and DNA damage, while zinc resupply promotes re-entry, without requiring p21.

Q-FADD: A mechanistic approach for modeling the accumulation of proteins at sites of DNA damage by free diffusion

The paper introduces a free diffusion model to quantify protein accumulation at DNA damage sites in live cells, applied to poly-ADP-ribose polymerases 1 and 2.