Author

A. E. Palmer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Biochemistry· 2 Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell signaling & trafficking· 4 Assay:imaging· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:fluorescence / live-cell microscopy· 2 Organism:mouse· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

A. J. Wierzba· 2 shared D. Gryko· 2 shared E. BRASELMANN· 2 shared L. J. Damon· 2 shared R. Jimenez· 2 shared R. T. Batey· 2 shared A. Ekrem· 1 shared C. D. Thomas· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

A. J. Wierzba

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Author profile →

8 papers

Recent·Most cited

Transient Zn2+ deficiency induces replication stress and compromises daughter cell proliferation

S. E. Holtzen, E. Navid, J. D. Kainov, A. E. Palmer

The paper shows that short Zn2+ deficiency during S-phase causes replication stress and impairs daughter cell proliferation, but not during other phases.

bioRxiv · Dec 8, 2023 · PreprintCell Biology

Targeting riboswitches with beta-axial substituted cobalamins

S. R. Lennon, A. J. Wierzba, S. H. Siwik, D. Gryko, A. E. Palmer, R. T. Batey

This study investigates interactions between eleven cobalamin derivatives and three cobalamin riboswitches, showing plasticity and selectivity in RNA-ligand binding with potential for antibiotic development.

bioRxiv · Dec 25, 2022 · PreprintBiochemistry

Single molecule microscopy to profile the effect of zinc status of transcription factor dynamics

L. J. Damon, J. Aaron, A. E. Palmer

This study uses single molecule microscopy to investigate how zinc status affects the dynamics and DNA binding of transcription factors.

bioRxiv · May 10, 2022Biophysics

Zn2+ influx activates ERK and Akt signaling pathways through a common mechanism

K. J. Anson, G. A. Corbett, A. E. Palmer

The paper quantifies Zn2+ fluctuations and their correlation with ERK and Akt signaling in single cells, showing activation through a common Ras node.

bioRxiv · Jul 27, 2020 · PreprintCell Biology

Structure-guided point mutations on FusionRed produce a brighter red fluorescent protein

S. Mukherjee, S. Hung, N. Douglas, P. Manna, C. D. Thomas, A. Ekrem, A. E. Palmer, R. Jimenez

The paper reports a brighter variant of the red fluorescent protein FusionRed, FusionRed-MQV, through structure-guided mutations that improve fluorescence properties.

bioRxiv · Apr 20, 2020 · PreprintBiophysics

Single Cell Analysis Reveals Multiple Requirements for Zinc in the Mammalian Cell Cycle

M. N. Lo, L. J. Damon, J. W. Tay, A. E. Palmer

This study shows that zinc deficiency causes cell cycle arrest and DNA damage, while zinc resupply promotes re-entry, without requiring p21.

bioRxiv · Aug 14, 2019Cell Biology

Detection and quantification of single mRNA dynamics with the Riboglow fluorescent RNA tag

E. BRASELMANN, T. J. Stasevich, K. Lyon, R. T. Batey, A. E. PALMER

The paper introduces Riboglow, a fluorescent RNA tag for detecting and tracking single mRNA molecules in live cells, and benchmarks it against the MS2 system.

bioRxiv · Jul 13, 2019 · PreprintCell Biology

Riboglow: a multicolor riboswitch-based platform for live cell imaging of mRNA and small non-coding RNA in mammalian cells

E. Braselmann, A. J. Wierzba, J. T. Polaski, M. Chrominski, Z. Holmes, S.-T. Hung, D. Batan, J. Wheeler, R. Parker, R. Jimenez, D. Gryko, R. T. T. Batey, A. E. Palmer

The paper introduces Riboglow, a multicolor riboswitch-based platform for live cell imaging of mRNA and small non-coding RNA in mammalian cells, showing it outperforms existing methods with a smaller RNA tag.

bioRxiv · Apr 9, 2018Biochemistry