Hypoxic gene expression in chronic hepatitis B infected patients is not observed in state-of-art in vitro and mouse infection models
P. J. Liu, J. M. Harris, E. Marchi, V. D'Arienzo, T. Michler, P. A. Wing, A. Magri, A. Otega-Prieto, M. Van de Klundert, J. Wettengel, D. Durantel, M. Dorner, P. Klenerman, U. Protzer, S. Giotis, J. A. McKeating
The paper shows hypoxia gene upregulation in chronic hepatitis B patients is not observed in in vitro or mouse models, suggesting inflammatory factors may drive this effect.
bioRxiv · Mar 27, 2020Microbiology