Author

J. Y. Fu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

J. A. Loo· 2 shared J. M. Muroski· 2 shared B. J. Mahoney· 1 shared C. Chang· 1 shared C. K. Sue· 1 shared G. H. Lu· 1 shared H. H. Nguyen· 1 shared H. Ton-That· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersMicrobiology

J. A. Loo

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Author profile →

4 papers

Recent·Most cited

The Basal and Major Pilins in the Corynebacterium diphtheriae SpaA Pilus Adopt Similar Structures that Competitively React with the Pilin Polymerase

C. K. Sue, N. A. Cheung, B. J. Mahoney, S. A. McConnell, J. M. Scully, J. Y. Fu, C. Chang, H. Ton-That, J. Loo, R. T. Clubb

The paper shows that SpaB and N-terminal SpaA (NSpaA) from Corynebacterium diphtheriae adopt similar structures and compete for a shared reaction intermediate in pilus assembly.

bioRxiv · Feb 23, 2023Biochemistry

Dynamic acylome reveals metabolite driven modifications in Syntrophomonas wolfei

J. Y. Fu, J. M. Muroski, M. A. Arbing, J. A. Salguero, N. Q. Wofford, M. J. McInerney, R. P. Gunsalus, J. A. Loo, R. R. O. Loo

The paper identifies acyl-lysine modifications in S. wolfei proteins linked to fatty acid degradation pathways using mass spectrometry-based proteomics.

bioRxiv · Jul 18, 2022Microbiology

Leveraging immonium ions for identifying and targeting acyl-lysine modifications in proteomic datasets

J. M. Muroski, J. Y. Fu, H. H. Nguyen, R. R. Ogorzalek Loo, J. A. Loo

This paper introduces a method using immonium ions to identify acyl-lysine modifications in proteomic datasets, demonstrating their utility in detecting and validating these modifications.

bioRxiv · Apr 20, 2020Biochemistry

Natural naphthoquinones isolated from Lithospermum erythrorhizon suppress dextran sulfate sodium-induced murine experimental colitis

W. X. Sun, H. W. Han, Z. Y. Wang, Z. L. Wen, M. K. Yang, Y. S. Wang, J. Y. Fu, L. Feng, X. H. Xu, T. M. Yin, X. M. Wang, G. H. Lu, J. L. Qi, H. Y. Lin, Y.- H. Yang

This study shows that shikonin and its derivatives reduce inflammation in DSS-induced colitis by inhibiting NLRP3 inflammasome and NF-κB pathways.

bioRxiv · Nov 4, 2019 · PreprintBiochemistry