Author

H. Ton-That

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Das· 2 shared C. Chang· 2 shared A. JoachimiakiD· 1 shared B. J. Mahoney· 1 shared C. K. Sue· 1 shared C. Wu· 1 shared D. Franklin· 1 shared J. Loo· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

A. Das

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular basis for dual functions in pilus assembly modulated by the lid of a pilus-specific sortase

C. Chang, H. Ton-That, J. Osipiuk, A. Joachimiak, A. Das, H. Ton-That

This study identifies the structural basis for the dual function of SrtC2 in pilus assembly by showing how its extended lid modulates polymerization and anchoring activities.

Journal of Biological Chemistry · Jun 1, 2024Peer-reviewedMicrobiology

The respiratory enzyme complex Rnf is vital for metabolic adaptation and virulence in Fusobacterium nucleatum

T. A. Britton, C. Wu, Y.-W. Chen, D. Franklin, Y. Chen, M. I. Camacho, T. T. Luong, A. Das, H. Ton-That

This paper identifies the Rnf complex as essential for Fusobacterium nucleatum's metabolic adaptation and virulence, showing its role in amino acid catabolism, biofilm formation, and pathogenesis in a mouse model.

bioRxiv · Jun 13, 2023 · PreprintMicrobiology

The Basal and Major Pilins in the Corynebacterium diphtheriae SpaA Pilus Adopt Similar Structures that Competitively React with the Pilin Polymerase

C. K. Sue, N. A. Cheung, B. J. Mahoney, S. A. McConnell, J. M. Scully, J. Y. Fu, C. Chang, H. Ton-That, J. Loo, R. T. Clubb

The paper shows that SpaB and N-terminal SpaA (NSpaA) from Corynebacterium diphtheriae adopt similar structures and compete for a shared reaction intermediate in pilus assembly.

bioRxiv · Feb 23, 2023Biochemistry