Structural basis of the human Scribble-Vangl2 association in health and disease
J. Y. How, R. Stephens, K. Y. B. Lim, P. O. Humbert, M. Kvansakul
This study determines the crystal structures of Scribble PDZ domains bound to Vangl2 and shows how mutations disrupt interactions with multiple signaling regulators.
bioRxiv · Oct 7, 2020Cell Biology