Author

J. Y. Shyy

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. R. Gingras· 1 shared B. Gongol· 1 shared C. Ballatore· 1 shared K. Oukoloff· 1 shared L. A. Sklar· 1 shared M. A. Lopez-Ramirez· 1 shared M. Bautista· 1 shared M. K. Haynes· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

A. R. Gingras

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintAug 23, 2019

Pharmacological inhibition of the heart of glass (HEG1)-Krev interaction trapped protein 1 (KRIT1) protein complex increases Kruppel-like Factors 4 and 2 (KLF4/2) expression in endothelial cells

M. A. Lopez-Ramirez, M. K. Haynes, P. Hale…·A. R. Gingras

This study identifies inhibitors of the HEG1-KRIT1 interaction that increase KLF4/2 expression in endothelial cells, leading to upregulation of thrombomodulin and downregulation of thrombospondin.

DOI 10.1101/744821

humanexperimental assay

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