Author

A. R. Gingras

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

M. A. Lopez-Ramirez· 2 shared B. Gongol· 1 shared B. Tan· 1 shared C. Ballatore· 1 shared F. Lagarrigue· 1 shared H. Sun· 1 shared J. Y. Shyy· 1 shared K. Oukoloff· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

M. A. Lopez-Ramirez

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2 papers

Recent·Most cited

The connection between Rap1 and Talin1 in CD4+ T Lymphocytes

F. Lagarrigue, B. Tan, Q. Du, Z. Fan, M. A. Lopez-Ramirez, A. R. Gingras, W. Qi, H. Sun

This study investigates the role of Rap1-talin1 interactions and RIAM in integrin activation in CD4+ T cells, showing that RIAM can substitute for Rap1 binding in some contexts.

bioRxiv · Sep 22, 2021 · PreprintCell Biology

Pharmacological inhibition of the heart of glass (HEG1)-Krev interaction trapped protein 1 (KRIT1) protein complex increases Kruppel-like Factors 4 and 2 (KLF4/2) expression in endothelial cells

M. A. Lopez-Ramirez, M. K. Haynes, P. Hale, K. Oukoloff, M. Bautista, B. Gongol, J. Y. Shyy, C. Ballatore, L. A. Sklar, A. R. Gingras

This study identifies inhibitors of the HEG1-KRIT1 interaction that increase KLF4/2 expression in endothelial cells, leading to upregulation of thrombomodulin and downregulation of thrombospondin.

bioRxiv · Aug 23, 2019 · PreprintBiochemistry