M. Bautista

Emerin oligomerization and nucleoskeletal coupling at the nuclear envelope regulate nuclear mechanics against stress

This study shows emerin forms oligomeric nanoclusters at the nuclear envelope, which regulate nuclear shape and mechanics under stress, and that mutations in emerin disrupt this process, leading to nuclear deformations in EDMD.

IL-1-conferred gene expression pattern in ERα+ BCa and AR+ PCa cells is intrinsic to ERα- BCa and AR- PCa cells and promotes cell survival

The paper identifies a 350-gene set conserved between HR+ and HR- BCa/PCa cells that promotes HR-independent survival and treatment resistance.

RELA is Sufficient to Mediate Interleukin-1 (IL-1) Repression of Androgen Receptor Expression and Activity in LNCaP Disease Progression Model

This study shows that RELA mediates IL-1 repression of AR mRNA and activity in PCa cells, with stronger effects in castration-resistant sublines.

Pharmacological inhibition of the heart of glass (HEG1)-Krev interaction trapped protein 1 (KRIT1) protein complex increases Kruppel-like Factors 4 and 2 (KLF4/2) expression in endothelial cells

This study identifies inhibitors of the HEG1-KRIT1 interaction that increase KLF4/2 expression in endothelial cells, leading to upregulation of thrombomodulin and downregulation of thrombospondin.

The importance of assigning responsibility during evaluation in order to increase student satisfaction from physical education classes: A model of structural equations

This study examines how assigning student responsibility in physical education evaluations affects satisfaction by linking it to motivational variables and psychological needs.