Author

J. Yanagawa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:organoid / primary culture· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Al Shihabi· 2 shared A. Davarifar· 2 shared A. Soragni· 2 shared E. Fung· 2 shared F. Hornicek· 2 shared H. T. L. Nguyen· 2 shared N. Bernthal· 2 shared N. Federman· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

A. Al Shihabi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The landscape of drug sensitivity and resistance in sarcoma

A. Al Shihabi, P. J. Tebon, H. T. L. Nguyen, J. Chantharasamee, S. Sartini, A. Davarifar, A. Y. Jensen, M. Diaz-Infante, H. Cox, A. Enrique-Gonzalez, S. Swearingen, N. Tavanaie, S. Dry, A. Singh, B. Chmielowski, , A. Soragni

This study uses patient-derived tumor organoids to identify drug sensitivity and resistance patterns in sarcoma, finding actionable treatment regimens for 59% of tested specimens.

bioRxiv · May 25, 2023Cancer Biology

Glucose deprivation promotes pseudo-hypoxia and de-differentiation in lung adenocarcinoma

P. Saggese, A. Pandey, E. Fung, A. Hall, J. Yanagawa, E. F. Rodriguez, T. R. Grogan, G. Giurato, G. Nassa, A. Salvati, A. Weisz, S. M. Dubinett, C. Scafoglio

This study shows glucose deprivation in lung adenocarcinoma causes de-differentiation and an aggressive phenotype through epigenetic changes and HIF1 activation.

bioRxiv · Jan 30, 2023Cancer Biology

Personalized chordoma organoids for drug discovery studies

A. Al Shihabi, A. Davarifar, H. T. L. Nguyen, N. Tavanaie, S. D. Nelson, J. Yanagawa, N. Federman, N. Bernthal, F. Hornicek, A. Soragni

This study establishes patient-derived chordoma organoids to identify effective targeted therapies, finding PI3K/mTOR, EGFR, and JAK2/STAT3 inhibitors as promising candidates.

bioRxiv · May 27, 2021Cancer Biology

Single-cell characterization of subsolid and solid lesions in the lung adenocarcinoma spectrum

J. Yanagawa, L. M. Tran, E. Fung, W. D. Wallace, A. E. Prosper, G. A. Fishbein, C. Shea, R. Hong, B. Liu, R. Salehi-Rad, J. Z. Deng, A. Gower, J. D. Campbell, S. A. Mazzilli, J. Beane, , S. M. Dubinett

The paper uses single-cell RNA sequencing to compare immune and non-immune cell features in subsolid, solid, and non-involved lung tissues, finding reduced cytolytic activity and increased regulatory T cells in subsolid lesions.

bioRxiv · Dec 25, 2020 · PreprintCancer Biology