Regulation of the MLH1-MLH3 endonuclease in meiosis
E. Cannavo, A. Sanchez, R. Anand, L. Ranjha, J. Hugener, C. Adam, A. Acharya, N. Weyland, X. Aran-Guiu, J.-B. Charbonnier, E. R. Hoffman, V. Borde, J. Matos, P. Cejka
This paper identifies the molecular mechanism by which the MLH1-MLH3 nuclease is activated in meiosis, showing its interaction with MutSγ, EXO1, RFC, and PCNA to process recombination intermediates.
bioRxiv · Feb 12, 2020Biochemistry