Epidermal maintenance of Langerhans cells relies on autophagy-regulated lipid metabolism
F. Arbogast, R. Sal-Carro, W. Boufenghour, Q. Frenger, D. Bouis, L. Filippi de la Palavesa, J.-D. Fauny, O. Griso, H. Puccio, R. Fima, T. Huby, E. L. Gautier, A. Molitor, R. Carapito, S. Bahram, , V. Flacher
This study shows that autophagy regulates lipid metabolism in Langerhans cells, preventing their depletion and ferroptosis in the epidermis.
bioRxiv · Sep 16, 2022Immunology