Author

J.-E. Messling

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Cell Biology· 1

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Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

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A. Williams· 1 shared B. Schumacher· 1 shared F. Heider· 1 shared W. Bloch· 1 shared

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2018-2018 · peak 1/yr

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1 shared paperCell Biology

A. Williams

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1 paper

Recent·Most cited

Activation of the endoplasmic reticulum unfolded protein response reverses an inflammation-like response to cytoplasmic DNA

A. Williams, F. Heider, J.-E. Messling, W. Bloch, B. Schumacher

The paper shows that in C. elegans, persistent cytoplasmic DNA causes tissue degeneration through impaired protein homeostasis, which can be reversed by activating the UPRER or using N-acetylglucosamine.

bioRxiv · Oct 11, 2018Cell Biology