A toxic friend: Genotoxic and mutagenic activity of the probiotic strain Escherichia coli Nissle 1917
J.-P. Nougayrede, C. Chagneau, J.-P. Motta, N. Bossuet-Greif, M. Belloy, F. Taieb, J.-J. Gratadoux, M. Thomas, P. Langella, E. Oswald
This study shows that the probiotic Escherichia coli Nissle 1917 produces the genotoxin colibactin, which induces DNA damage and mutagenesis in vitro and in vivo.
bioRxiv · Mar 22, 2021Microbiology