Outer membrane vesicles produced by pathogenic strains of Escherichia coli block autophagic flux and exacerbate inflammasome activation
L. DAVID, F. Taieb, M. Penary, P.-J. Bordignon, R. Planes, S. Bagayoko, V. Duplan-Eche, E. Meunier, E. Oswald
The paper shows that OMVs from pathogenic E. coli block autophagic flux and enhance inflammasome activation, contributing to disease severity.
bioRxiv · Apr 20, 2021Microbiology