Author

J.-P. Nougayrede

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:E. coli· 3 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

E. Oswald· 5 shared C. Massip· 3 shared C. V. Chagneau· 3 shared N. Bossuet-Greif· 3 shared P. Branchu· 3 shared C. Chagneau· 2 shared J.-P. Motta· 2 shared Y. Ogura· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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5 shared papersMicrobiology

E. Oswald

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Author profile →

5 papers

Recent·Most cited

HlyF, an underestimated virulence factor of uropathogenic Escherichia coli

C. V. Chagneau, D. Payros, A. Goman, C. Goursat, L. David, M. Okuno, P.-J. Bordignon, C. Seguy, C. Massip, P. Branchu, Y. Ogura, J.-P. Nougayrede, M. Marenda, E. Oswald

The paper identifies HlyF as a virulence factor in UPEC strains associated with severe UTIs and urosepsis, showing its link to plasmid-mediated virulence and antimicrobial resistance.

bioRxiv · Apr 27, 2023 · PreprintMicrobiology

Oxygen concentration modulates colibactin production

N. Bossuet, C. Guyonnet, C. Chagneau, M. Tang-Fichaux, M. Penary, D. Loubet, P. Branchu, E. Oswald, J.-P. Nougayrede

This study shows that colibactin production in E. coli is maximal under anoxic conditions and decreases with oxygen concentration, suggesting adaptation to the intestinal environment.

bioRxiv · Jun 20, 2022Microbiology

Insights into the acquisition of the pks island and production of colibactin in the Escherichia coli population

F. Auvray, A. Perrat, Y. Arimizu, C. V. Chagneau, N. Bossuet-Greif, C. Massip, H. Brugere, J.-P. Nougayrede, T. Hayashi, P. Branchu, Y. Ogura, E. Oswald

This study identifies the distribution and functionality of the pks island in E. coli strains, showing its presence across multiple phylogroups and its role in colibactin production.

bioRxiv · Apr 13, 2021Microbiology

A toxic friend: Genotoxic and mutagenic activity of the probiotic strain Escherichia coli Nissle 1917

J.-P. Nougayrede, C. Chagneau, J.-P. Motta, N. Bossuet-Greif, M. Belloy, F. Taieb, J.-J. Gratadoux, M. Thomas, P. Langella, E. Oswald

This study shows that the probiotic Escherichia coli Nissle 1917 produces the genotoxin colibactin, which induces DNA damage and mutagenesis in vitro and in vivo.

bioRxiv · Mar 22, 2021Microbiology

Uropathogenic E. coli induces DNA damage in the bladder

C. V. Chagneau, C. Massip, N. Bossuet-Greif, C. Fremez, J.-P. Motta, A. Shima, C. Besson, P. Le Faouder, N. Cenac, M.-P. Roth, H. Coppin, M. Fontanie, P. Martin, J.-P. Nougayrede, E. Oswald

The paper reports colibactin production in human UTIs and its genotoxic effects on bladder cells, linking it to potential bladder cancer risk.

bioRxiv · May 7, 2020 · PreprintMicrobiology