ESRP2-microRNA-122 axis directs the postnatal onset of liver polyploidization and maturation
Sushant Bangru, Jackie Chen, Nicholas Baker, Diptatanu Das, Ullas Valiya Chembazhi, Jessica M. Derham, Sandip Chorghade, Waqar Arif, Frances Alencastro, Andrew W. Duncan, Russ P. Carstens, Auinash Kalsotra
This study identifies the ESRP2-miR-122 axis as critical for postnatal liver polyploidization and maturation through RNA processing and cytokinesis regulation.
bioRxiv · Jul 6, 2024 · PreprintDevelopmental Biology