Russ P. Carstens

Functional analysis of ESRP1/2 gene variants and CTNND1 isoforms in orofacial cleft pathogenesis

The paper functionally tests ESRP1/2 variants and CTNND1 isoforms in orofacial cleft models, finding some variants are benign and showing CTNND1's role in palatogenesis.

ESRP2-microRNA-122 axis directs the postnatal onset of liver polyploidization and maturation

This study identifies the ESRP2-miR-122 axis as critical for postnatal liver polyploidization and maturation through RNA processing and cytokinesis regulation.

The Global Protein-RNA Interaction map of Epithelial Splicing Regulatory Protein 1 defines a post-transcriptional program that is essential for epithelial cell function

The paper identifies ESRP1's genome-wide binding sites and shows its role in splicing regulation and post-transcriptional functions in epithelial cells.

Requirement of Irf6 and Esrp1/2 in frontonasal and palatal epithelium to regulate craniofacial and palate morphogenesis in mouse and zebrafish

This study investigates the role of Irf6 and Esrp1/2 in craniofacial development across mouse and zebrafish, identifying their expression patterns and genetic interactions in cleft formation.

Cleft lip and cleft palate (CL/P) in Esrp1 KO mice is associated with alterations in Wnt signaling and epithelial-mesenchymal crosstalk

The paper investigates the role of Esrp1 in cleft lip and palate development in mice, identifying altered Wnt signaling and epithelial-mesenchymal interactions as key factors.