Sushant Bangru

This study quantifies spatial asymmetry in zebrafish pectoral fin regeneration, revealing differential gene expression and signaling dynamics between anterior and posterior regions.

The paper identifies hoxb5a as a critical regulator of spinal cord regeneration in zebrafish by analyzing transcriptional and microenvironmental differences between successful and failed regeneration cases.

The paper shows that MALAT1 long noncoding RNA forms condensates with splicing factors to regulate hypoxia-induced alternative splicing near nuclear speckles.

The paper identifies genetic mutations that affect regeneration programs in zebrafish, showing that these programs can buffer developmental defects.

The paper identifies dysregulated RNA splicing in alcohol-associated liver disease as a cause of regeneration failure, highlighting ESRP2 deficiency and its impact on key signaling pathways.

This study identifies the ESRP2-miR-122 axis as critical for postnatal liver polyploidization and maturation through RNA processing and cytokinesis regulation.

This study identifies PTBP1 as essential for intestinal stem cell survival and stemness by regulating gene expression through post-transcriptional mechanisms.

This study uses single-cell transcriptomics to track liver cell transitions during regeneration, revealing metabolic and proliferative dynamics in mouse liver.

This study identifies cell types and transcriptional heterogeneity in the corneal epithelium of Xenopus larvae through single-cell RNA sequencing, revealing novel genes and regulatory networks involved in differentiation and regeneration.

The paper introduces SimiC, a method for inferring gene regulatory networks per cell phenotype and comparing them across conditions, revealing regulatory dynamics missed by single GRN approaches.

This study identifies overexpression of a non-muscle RBFOX2 isoform as a cause of cardiac conduction defects in myotonic dystrophy by inducing arrhythmia and altering ion channel splicing.