A Bayesian analysis of the association between Leukotriene A4 Hydrolase genotype and survival probability of tuberculous meningitis patients treated with adjunctive dexamethasone
Laura J. Whitworth, Jacob Coxon, Arjan van Laarhoven, Nguyễn Thụy Thương Thương, Sofiati Dian, Bachti Alisjahbana, Ahmad Rizal Ganiem, Reinout van Crevel, Guy Edward Thwaites, Mark A. Troll, Paul H. Edelstein, Roger Sewell, Lalita Ramakrishnan
The paper uses Bayesian analysis to show the LTA4H TT genotype improves survival in TBM patients in Vietnam and Indonesia, but only when disease severity is not the primary cause of mortality.
bioRxiv · Aug 3, 2020 · PreprintMolecular Biology