Author

Arjan van Laarhoven

Radboud University NijmegenORCID 0000-0002-6607-4075Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:Bayesian inference· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Research Focus:GWAS / association mapping· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Bachti AlisjahbanaiD· 3 shared Reinout van CreveliD· 3 shared Ahmad Rizal GaniemiD· 2 shared Sofiati DianiD· 2 shared Todia Pediatama SetiabudiawaniD· 2 shared Agnes R. Indrati· 1 shared Anca‐Lelia RizaiD· 1 shared Ayesha J. VerralliD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersGenetics

Bachti AlisjahbanaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Sequencing whole genomes of the West Javanese population in Indonesia reveals novel variants and improves imputation accuracy

Edwin Ardiansyah, Anca‐Lelia Riza, Sofiati Dian, Ahmad Rizal Ganiem, Bachti Alisjahbana, Todia Pediatama Setiabudiawan, Arjan van Laarhoven, Reinout van Crevel, Vinod Kumar

The paper improves imputation accuracy for Indonesians by adding West Javanese whole genome sequencing data to existing reference panels.

Frontiers in Genetics · Feb 7, 2025Peer-reviewedGenetics

Immune correlates of early clearance of Mycobacterium tuberculosis among tuberculosis household contacts in Indonesia

Todia Pediatama Setiabudiawan, Lika Apriani, Ayesha J. Verrall, Fitria Utami, Marion Schneider, Agnes R. Indrati, Pauline Phoebe Halim, Paulina Kapłonek, Hadar Malca, Jessica Shih-Lu Lee, Simone J.C.F.M. Moorlag, L. Charlotte J. de Bree, Vera P. Mourits, Leo A. B. Joosten, Mihai Gheorghe Netea, , Reinout van Crevel

The paper investigates immune correlates of early Mtb clearance in TB household contacts, finding that BCG vaccination is linked to enhanced innate immune responses rather than adaptive immunity.

Nature Communications · Jan 2, 2025Peer-reviewedImmunology

A Bayesian analysis of the association between Leukotriene A4 Hydrolase genotype and survival probability of tuberculous meningitis patients treated with adjunctive dexamethasone

Laura J. Whitworth, Jacob Coxon, Arjan van Laarhoven, Nguyễn Thụy Thương Thương, Sofiati Dian, Bachti Alisjahbana, Ahmad Rizal Ganiem, Reinout van Crevel, Guy Edward Thwaites, Mark A. Troll, Paul H. Edelstein, Roger Sewell, Lalita Ramakrishnan

The paper uses Bayesian analysis to show the LTA4H TT genotype improves survival in TBM patients in Vietnam and Indonesia, but only when disease severity is not the primary cause of mortality.

bioRxiv · Aug 3, 2020 · PreprintMolecular Biology