Neuroprotective effects of Canagliflozin: lessons from aged genetically diverse UM-HET3 mice.
Hashan S. M. Jayarathne, Lucas Kniess Debarba, Jacob J. Jaboro, Brett C. Ginsburg, Richard A. Miller, Marianna Sadagurski
This study shows that Canagliflozin improves central insulin sensitivity and reduces neuroinflammation in aged male mice but not females, suggesting sex-specific neuroprotective effects.
Aging Cell · Jun 15, 2022Peer-reviewedNeuroscience