Author

Firoozeh Nafar

Memorial University of Newfoundland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

Jessica C. BarroniD· 4 shared Matthew P. ParsonsiD· 4 shared Emily P. HurleyiD· 3 shared Bandhan Mukherjee· 2 shared Craig Stephen MooreiD· 2 shared Jocelyn R. Barnes· 2 shared Samantha J. CarewiD· 2 shared Christiana M. Kennedy· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersNeuroscience

Jessica C. BarronORCID

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Author profile →

4 papers

Recent·Most cited

Striatal neuron excitability is regulated by huntingtin in the adult brain

Jessica C. Barron, Meghan L. Greenland, Samantha J. Carew, Fatemeh Ashrafganjoie, Emily P. Hurley, Christiana M. Kennedy, Firoozeh Nafar, Craig Stephen Moore, Matthew P. Parsons

This study shows that loss of wild-type huntingtin in adult striatal neurons reduces excitability and causes neuroinflammation without affecting tissue structure or motor behavior.

eNeuro · May 28, 2026Peer-reviewedNeuroscience

Huntingtin is essential for synaptic plasticity in the adult hippocampus

Jessica C. Barron, Laura J. Dawson, Samantha J. Carew, Mackenzie C. Grace, Kelsie A Senior, Katelyn C Ryan, Firoozeh Nafar, Craig Stephen Moore, Jacqueline J. Blundell, Matthew P. Parsons

This study shows that wild-type huntingtin (wtHTT) is essential for synaptic plasticity in the adult hippocampus, as its loss impairs long-term potentiation and post-tetanic potentiation.

Neurobiology of Disease · Jan 22, 2025Peer-reviewedNeuroscience

Atypical NMDA Receptors Limit Synaptic Plasticity in the Adult Ventral Hippocampus

Emily P. Hurley, Bandhan Mukherjee, Lisa Z. Fang, Jocelyn R. Barnes, Jessica C. Barron, Firoozeh Nafar, Michiru Hirasawa, Matthew P. Parsons

This study shows that GluN3A persistence in the adult ventral hippocampus reduces glutamate release and NMDAR-dependent long-term potentiation, impacting emotional processing.

Journal of Neuroscience · Sep 10, 2024Peer-reviewedNeuroscience

Asymmetric dysregulation of glutamate dynamics across the synaptic cleft in a mouse model of Alzheimer disease

Kyle J. Brymer, Emily P. Hurley, Jessica C. Barron, Bandhan Mukherjee, Jocelyn R. Barnes, Firoozeh Nafar, Matthew P. Parsons

The paper shows that GLT-1 dysfunction disproportionately affects presynaptic glutamate clearance in an Alzheimer's mouse model, highlighting presynaptic vulnerability.

bioRxiv · Apr 21, 2022 · PreprintNeuroscience