Author

Samantha J. Carew

Memorial University of NewfoundlandORCID 0000-0002-5691-9871Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Craig Stephen MooreiD· 2 shared Firoozeh Nafar· 2 shared Jessica C. BarroniD· 2 shared Matthew P. ParsonsiD· 2 shared Christiana M. Kennedy· 1 shared Emily P. HurleyiD· 1 shared Fatemeh Ashrafganjoie· 1 shared Jacqueline J. Blundell· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersNeuroscience

Craig Stephen MooreORCID

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2 papers

Recent·Most cited

NeuroscienceeNeuroPeer-reviewedMay 28, 2026

Striatal neuron excitability is regulated by huntingtin in the adult brain

Jessica C. Barron, Meghan L. Greenland, Samantha J. Carew…·Matthew P. Parsons

This study shows that loss of wild-type huntingtin in adult striatal neurons reduces excitability and causes neuroinflammation without affecting tissue structure or motor behavior.

2 citations

mouseexperimental assay

𝕏 PostBluesky

NeuroscienceNeurobiology of DiseasePeer-reviewedJan 22, 2025

Huntingtin is essential for synaptic plasticity in the adult hippocampus

Jessica C. Barron, Laura J. Dawson, Samantha J. Carew…·Matthew P. Parsons

This study shows that wild-type huntingtin (wtHTT) is essential for synaptic plasticity in the adult hippocampus, as its loss impairs long-term potentiation and post-tetanic potentiation.

5 citations

mouseexperimental assay

𝕏 PostBluesky