Hemoglobin as a peroxidase and drug target for oxidative stress-related diseases
Woojin Won, Elijah Hwejin Lee, Lizaveta Gotina, Heejung Chun, Jae-Hun Lee, Uiyeol Park, Daeun Kim, Tai Young Kim, Ji Won Choi, Yoowon Kim, Sun Jun Park, Mridula Bhalla, Jiwoon Lim, Jong Hyun Park, Soo Jin Oh, , Changjoon Justin Lee
This paper identifies hemoglobin as a peroxidase with therapeutic potential for oxidative stress-related diseases and presents KDS12025 as a drug candidate that enhances its activity.
bioRxiv · May 21, 2024 · PreprintNeuroscience