Author

Tai Young Kim

Institute for Basic Science

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:electronic health records· 1

Frequent Co-Authors

Changjoon Justin LeeiD· 4 shared Hoon RyuiD· 2 shared Jiwoon LimiD· 2 shared Minwoo Wendy JangiD· 2 shared Mridula BhallaiD· 2 shared Uiyeol Park· 2 shared Ae Nim PaeiD· 1 shared Ah Reum HaniD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersNeuroscience

Changjoon Justin LeeORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Hyperactivation of the AXL-ICD/SIRT2 axis by Amyloid-β impairs astrocytic autophagic flux and exacerbates neuroinflammation

Tai Young Kim, Mridula Bhalla, Uiyeol Park, Seung Jae Hyeon, In‐Young Hwang, Youngsuk Seo, Wongu Youn, Jin-A Lee, Jung-Hee Lee, Boyoung Lee, Hoon Ryu, Changjoon Justin Lee

This study identifies the AXL-ICD/SIRT2 axis as a mechanism by which amyloid-β impairs astrocytic autophagy and exacerbates neuroinflammation in Alzheimer's disease.

bioRxiv · Aug 31, 2026 · PreprintNeuroscience

Hemoglobin as a peroxidase and drug target for oxidative stress-related diseases

Woojin Won, Elijah Hwejin Lee, Lizaveta Gotina, Heejung Chun, Jae-Hun Lee, Uiyeol Park, Daeun Kim, Tai Young Kim, Ji Won Choi, Yoowon Kim, Sun Jun Park, Mridula Bhalla, Jiwoon Lim, Jong Hyun Park, Soo Jin Oh, , Changjoon Justin Lee

This paper identifies hemoglobin as a peroxidase with therapeutic potential for oxidative stress-related diseases and presents KDS12025 as a drug candidate that enhances its activity.

bioRxiv · May 21, 2024 · PreprintNeuroscience

Astrocytic Gapjinc (TMEM43) modulates gap junction networks by facilitating transjunctional potentials

Minwoo Wendy Jang, Ki‐Jung Kim, Jiwoon Lim, Daeun Kim, Yongmin Mason Park, Tai Young Kim, Woo Suk Roh, Young‐Eun Han, Joungha Won, Jae‐Hun Lee, Eunjin Shin, Ah Reum Han, Ho Min Kim, Kyung‐Seok Han, Changjoon Justin Lee

This study identifies TMEM43 as a pH-sensing cation channel that modulates gap junction networks in the hippocampus, preventing neuronal hyperexcitability and supporting memory retrieval.

bioRxiv · Nov 8, 2022 · PreprintNeuroscience

Mutations in TMEM43 cause autosomal dominant auditory neuropathy spectrum disorder via interaction with Connexin-mediated passive conductance channels

Minwoo Wendy Jang, Doo‐Yi Oh, Eunyoung Yi, Xuezhong Liu, Jie Ling, Nayoung Kim, Kushal Sharma, Tai Young Kim, Seungmin Lee, Ah Reum Kim, Min Young Kim, Min A Kim, Mingyu Lee, Jin Hee Han, Jae Joon Han, , Byung Yoon Choi

This study identifies TMEM43 mutations as a cause of autosomal dominant auditory neuropathy spectrum disorder by showing their interaction with Connexin-mediated channels in cochlear glia-like supporting cells.

Proceedings of the National Academy of Sciences · May 28, 2021Peer-reviewedGenetics