Structural Tuning of HEWL Amyloid Polymorphs Enhances Antibacterial Activity Against Gram-Positive and Gram-Negative Pathogens
Sanjay Kisan Metkar, Annie Scutte, Jamel Ali, Ayyalusamy Ramamoorthy
This study shows that structurally distinct amyloid polymorphs of HEWL have enhanced antibacterial activity compared to native HEWL, with flexible fibrils showing the strongest activity against multiple bacterial strains.
bioRxiv · Jul 14, 2026 · PreprintBioengineering