Portable transcranial therapeutic ultrasound enhances targeted gene delivery for Parkinson's disease: from rodent models to non-human primates
Alec J. Batts, Robin Ji, Sua Bae, Fotios N. Tsitsos, Sergio Jiménez-Gambín, Nancy Kwon, Samantha L. Gorman, Deny Tsakri, Rebecca Lynn Noel, Jonas Bendig, Daniella Amanda Jimenez, Melody R. DiBenedetto, Sofia A. Del Castillo, Filimon B. Keleta, James Caicedo, , Elisa E. Konofagou
Portable therapeutic ultrasound enhanced AAV9 delivery to the brain in mice and rhesus macaques compared to systemic injection alone.
bioRxiv · Mar 2, 2025 · PreprintBioengineering