Author

James I McDonald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Cesar Sanchez· 1 shared Jeff F Hiken· 1 shared Jeremy Hoog· 1 shared John R Edwards· 1 shared Keith F Decker· 1 shared Kyle L Jung· 1 shared Margaret Akinhanmi· 1 shared Matthew J Ellis· 1 shared

Activity by Year

2016-2016 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Cesar Sanchez

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Epigenetic activation of the prostaglandin receptor EP4 promotes resistance to endocrine therapy for breast cancer

Jeff F Hiken, James I McDonald, Keith F Decker, Cesar Sanchez, Jeremy Hoog, Nathan D VanderKraats, Kyle L Jung, Margaret Akinhanmi, Matthew J Ellis, John R Edwards

The paper identifies epigenetic activation of PTGER4 as a mechanism promoting resistance to aromatase inhibitors in breast cancer and suggests it as a potential therapeutic target.

bioRxiv · Jun 2, 2016Cancer Biology