Author

Jan Gregrowicz

California Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Michael B. ElowitziD· 2 shared Bo GuiD· 1 shared Brice Graham Hendrickson· 1 shared Bryan Anggito· 1 shared Gal ManellaiD· 1 shared Hengyu LiiD· 1 shared James M. LintoniD· 1 shared Ron HadasiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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2 shared papersSystems Biology

Michael B. ElowitzORCID

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2 papers

Recent·Most cited

Adenylyl cyclases combinatorially integrate opposing dopamine receptor signals

Jan Gregrowicz, Michael B. Elowitz

The paper shows that adenylyl cyclases integrate opposing dopamine receptor signals in neurons, with AC isoform expression determining signal outcomes.

bioRxiv · Jul 13, 2026 · PreprintSystems Biology

Programmable pathway profiles reveal signaling principles of TGF-β superfamily receptors

Bo Gu, James M. Linton, Brice Graham Hendrickson, Hengyu Li, Ron Hadas, Gal Manella, Jan Gregrowicz, Bryan Anggito, Rong Lu, Michael B. Elowitz

The paper develops Pathway Sculptor to systematically modulate TGF-β receptor subsets, revealing functional interactions between BMP and TGF-β pathways and their collaborative signaling mechanisms.

bioRxiv · Jun 15, 2025 · PreprintSynthetic Biology