Author
California Institute of TechnologyORCID 0000-0002-6711-4139Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Rongrong Du, Michael J. Flynn, Karan Mahe…·Michael B. Elowitz
The paper introduces DIMMERs, miRNA-based circuits that enable precise, tunable control of transgene expression across cell types, improving gene therapy and research applications.
Bo Gu, James M. Linton, Brice Graham Hendrickson…·Michael B. Elowitz
The paper develops Pathway Sculptor to systematically modulate TGF-β receptor subsets, revealing functional interactions between BMP and TGF-β pathways and their collaborative signaling mechanisms.
Andrew C. Lu, Lukas Moeller, Stephen Moore…·Michael B. Elowitz
This paper engineers protease-based protein circuits that selectively kill RAS-mutant cancer cells and suppress tumors, showing resistance reduction and cytotoxicity independent of oncogene addiction.