Author

Jan Ostendorf

University of Copenhagen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Birthe Brandt KragelundiD· 1 shared Emil E. TranchantiD· 1 shared Henriette Elisabeth AutzeniD· 1 shared Jesper Foged HavelundiD· 1 shared Lara Kristin SachiD· 1 shared Lukas P. FeileniD· 1 shared Milena Rankilde Lilac· 1 shared Nils Joakim FærgemaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Birthe Brandt KragelundORCID

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1 paper

Recent·Most cited

Integrative structural analysis of the human endosomal Na⁺/H⁺ exchanger NHE6 reveals a lipid-stabilized intracellular gate and a disordered C-terminus

Lukas P. Feilen, Emil E. Tranchant, Milena Rankilde Lilac, Lara Kristin Sach, Jesper Foged Havelund, Jan Ostendorf, Nils Joakim Færgeman, Stine F. Pedersen, Birthe Brandt Kragelund, Henriette Elisabeth Autzen

The paper presents the cryo-EM structure of HsNHE6, revealing its dimeric architecture, ion-binding site, and lipid-stabilized gate, along with insights into its disordered C-terminus and functional roles in ion exchange and disease.

bioRxiv · Jul 21, 2025 · PreprintBiochemistry