Lara Kristin Sach

The paper presents the cryo-EM structure of HsNHE6, revealing its dimeric architecture, ion-binding site, and lipid-stabilized gate, along with insights into its disordered C-terminus and functional roles in ion exchange and disease.

This study shows that mice do not uniformly express defensive behaviors when exposed to predators, instead showing context-dependent and variable responses.

This paper identifies a hypothalamus-brainstem circuit that prioritizes safety over essential needs by modulating locomotion behavior.