Non-decameric NLRP3 forms an MTOC-independent inflammasome
Maria Mateo Tortola, Inga V. Hochheiser, Jelena Grga, Jana S. Mueller, Matthias Geyer, Alexander N.R. Weber, Ana Tapia‐Abellán
The paper identifies two distinct NLRP3 activation pathways, one dependent on decameric cage formation and another independent of the MTOC and TGN.
bioRxiv · Jul 7, 2023 · PreprintMolecular Biology