Optogenetic manipulation of second messengers in neurons and cardiomyocytes with microbial rhodopsins and adenylyl cyclase
Hanako Hagio, Shiori Hosaka, Wataru Koyama, Aysenur Deniz Song, Janchiv Narantsatsral, Kōji Matsuda, Takashi Shimizu, Shoko Hososhima, Satoshi P. Tsunoda, Hideki Kandori, Masahiko Hibi
The paper demonstrates the use of microbial rhodopsins and adenylyl cyclases to control second messengers in zebrafish neurons and cardiomyocytes, revealing their roles in locomotion and cardiac function.
eLife · Jul 31, 2023Peer-reviewedNeuroscience