Takashi Shimizu

Conserved and divergent programs govern cerebellar output neuron development in zebrafish

This study identifies conserved and divergent developmental programs for cerebellar output neurons in zebrafish, showing shared origins with other vertebrates and unique mechanisms for eurydendroid cell organization.

Optogenetic manipulation of second messengers in neurons and cardiomyocytes with microbial rhodopsins and adenylyl cyclase

The paper demonstrates the use of microbial rhodopsins and adenylyl cyclases to control second messengers in zebrafish neurons and cardiomyocytes, revealing their roles in locomotion and cardiac function.

Optogenetic manipulation of Gq-and Gi/o-coupled receptor signaling in neurons and heart muscle cells

The paper develops optogenetic tools using animal G protein-coupled bistable rhodopsins to control Gq and Gi/o signaling in neurons and cardiomyocytes, showing their utility in vivo.

Pax3 and Pax7 function in combination with Mitf to generate melanophores and xanthophores in medaka and zebrafish

This study shows that Pax3 and Pax7 work with Mitf to control melanophore and xanthophore development in medaka and zebrafish, revealing a conserved but complex regulatory network.

Foxp- and Skor-family proteins control differentiation of Purkinje cells from Ptf1a and Neurogenin1-expressing progenitors in zebrafish

This study identifies Foxp1b/4 and Skor1b/2 as key transcriptional regulators controlling Purkinje cell differentiation from ptf1a/neurogenin1-expressing progenitors in zebrafish.

Gsx2 is involved in specification of neurons in the inferior olivary nuclei from Ptf1a-expressing neuronal progenitors in zebrafish

This study shows that gsx2 mediates rostro-caudal positional signals to specify inferior olivary neurons from ptf1a-expressing progenitors in zebrafish.