Shared PRAME Epitopes are T-Cell Targets in NUT Carcinoma
Jeffrey Lee Jensen, Sara K. Peterson, Maria J. Sambade, Jessica Alley, Shawn Yu, Tomoaki Kinjo, Sarah Bennett, Steven P. Vensko II, Mitra Shabrang, Johnathan D. DeBetta, Julie K. Geyer, Brandon A. Price, Kwangok P. Nickel, Randall J. Kimple, Rishi Sury Kotecha, , B. V. Vincent
This study identifies PRAME as a therapeutic target in NUT carcinoma, showing its high expression and susceptibility to T-cell mediated cytotoxicity via PRAME epitopes presented by HLA Class I molecules.
Journal for ImmunoTherapy of Cancer · Feb 1, 2026Peer-reviewedCancer Biology