Ian J. Davis

The paper introduces vmwhere, a tool for analyzing tetrameric microsatellites from long-read sequencing data, and shows its application in linking GGAA repeat structure to chromatin state in Ewing sarcoma.

This study identifies PRAME as a therapeutic target in NUT carcinoma, showing its high expression and susceptibility to T-cell mediated cytotoxicity via PRAME epitopes presented by HLA Class I molecules.

This study shows that PRC2 maintains neural identity in cerebellar progenitors and medulloblastoma, but its disruption does not block medulloblastoma progression.

The paper identifies how CHD4/NuRD is recruited to cardiac gene loci via interactions with GATA4, NKX2-5, and TBX5, revealing its role in repressing non-cardiac gene programs during heart development.

This study uses optogenetic control of Set2 in yeast to show rapid, transcription-dependent H3K36me3 deposition and transcription-independent, stochastic demethylation.

The paper compares manual and automated taxonomic assignment methods for bacterial genomes from the canine oral cavity, finding GTDB to be less subjective and labor-intensive.