Tomoaki Kinjo

The paper introduces Caterpie, a live cell labeling system using split fluorescent proteins to enable high-fidelity identification of multiple cell populations with 97% accuracy.

This study compares mRNA and yeast display technologies for evaluating ML-designed miniprotein binders, finding mRNA display better enriches slow dissociating binders and achieves higher library coverage.

This study identifies PRAME as a therapeutic target in NUT carcinoma, showing its high expression and susceptibility to T-cell mediated cytotoxicity via PRAME epitopes presented by HLA Class I molecules.

This paper designs orthogonal TCR β interfaces to prevent mispairing in dual-TCR therapeutics, achieving high pairing fidelity and demonstrating enhanced potency in targeting cancer antigens.