Author

Jason M. Müller

University of Cologne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Achim TreschiD· 2 shared Katharina MoosiD· 2 shared Andreas MayeriD· 1 shared Elisabeth AltendorferiD· 1 shared Kerstin C. Maier· 1 shared Kristina ŽumeriD· 1 shared Susanne Freier· 1 shared Till BaariD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 19 mutual co-author links

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2 shared papersBioinformatics

Achim TreschORCID

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2 papers

Recent·Most cited

Halfpipe: a tool for analyzing metabolic labeling RNA-seq data to quantify RNA half-lives

Jason M. Müller, Elisabeth Altendorfer, Susanne Freier, Katharina Moos, Andreas Mayer, Achim Tresch

Halfpipe quantifies RNA half-lives from metabolic labeling RNA-seq data, showing similar half-lives for constantly expressed RNAs in mitosis and G1 phase.

NAR Genomics and Bioinformatics · Jan 7, 2025Peer-reviewedBioinformatics

Nuclear export is a limiting factor in eukaryotic mRNA metabolism

Jason M. Müller, Katharina Moos, Till Baar, Kerstin C. Maier, Kristina Žumer, Achim Tresch

This study quantifies mRNA synthesis, nuclear export, and degradation rates genome-wide, finding nuclear export is slow and cytosolic degradation is fast, with some transcripts using alternative export pathways.

PLoS Computational Biology · May 16, 2024Peer-reviewedSystems Biology