Author

Till Baar

University of CologneORCID 0000-0002-6744-1463Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Achim TreschiD· 2 shared Chrysa NikopoulouiD· 1 shared David KöhleriD· 1 shared Jason M. Müller· 1 shared Katharina MoosiD· 1 shared Kerstin C. Maier· 1 shared Kristina ŽumeriD· 1 shared Matthias C. SchmidiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSystems Biology

Achim TreschORCID

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2 papers

Recent·Most cited

Nuclear export is a limiting factor in eukaryotic mRNA metabolism

Jason M. Müller, Katharina Moos, Till Baar, Kerstin C. Maier, Kristina Žumer, Achim Tresch

This study quantifies mRNA synthesis, nuclear export, and degradation rates genome-wide, finding nuclear export is slow and cytosolic degradation is fast, with some transcripts using alternative export pathways.

PLoS Computational Biology · May 16, 2024Peer-reviewedSystems Biology

Dimension Reduction by Spatial Components Analysis Improves Pattern Detection in Multivariate Spatial Data

Niklas Kleinenkuhnen, David Köhler, Till Baar, Chrysa Nikopoulou, Vangelis Kondylis, Matthias C. Schmid, Peter Tessarz, Achim Tresch

The paper introduces SPACO, a method for dimension reduction in spatial transcriptomics data that improves pattern detection by maximizing Moran's I and outperforms PCA.

bioRxiv · Oct 12, 2023 · PreprintBioinformatics