Andreas Mayer

ELOF1 is a core component of the promoter-proximal paused RNA polymerase II complex

This study identifies ELOF1 as a critical factor enhancing promoter-proximal RNA polymerase II pausing, showing its role in counteracting TFIIF effects.

Nucleolus transformation and Pol1 activity pattern dual transcriptomes of neuronal subtype identity

The paper identifies that nucleolar restructuring and Pol1 activity patterns are linked to neuronal subtype identity through dual rRNA-mRNA transcriptomes in developing neocortex.

Halfpipe: a tool for analyzing metabolic labeling RNA-seq data to quantify RNA half-lives

Halfpipe quantifies RNA half-lives from metabolic labeling RNA-seq data, showing similar half-lives for constantly expressed RNAs in mitosis and G1 phase.

Deciphering the consequence of deep intronic variants: a progeroid syndrome caused by a TAPT1 mutation is revealed by combined RNA/SI-NET sequencing

The paper identifies a deep intronic TAPT1 mutation causing progeroid syndrome using RNA-seq and homozygosity mapping, showing it leads to exon skipping and protein-null allele.