Author

Jathin Kollarapu

Saint Louis University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew Huy NguyeniD· 1 shared Ankan Kumar BhadraiD· 1 shared Denise M. SmithiD· 1 shared Don Ashley O. MalabanaiD· 1 shared Geetika AggarwaliD· 1 shared Joel Jihwan HwangiD· 1 shared Nitya NagarajaniD· 1 shared Subhashis BanerjeeiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperNeuroscience

Andrew Huy NguyenORCID

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Author profile →

1 paper

Recent·Most cited

Progranulin deficiency promotes neuroinflammation through cathepsin B-mediated activation of the NLRP3 inflammasome

Geetika Aggarwal, Subhashis Banerjee, Ankan Kumar Bhadra, Joel Jihwan Hwang, Don Ashley O. Malabana, Nitya Nagarajan, Denise M. Smith, Jathin Kollarapu, Andrew Huy Nguyen

This study shows that progranulin deficiency increases NLRP3 inflammasome activity via cathepsin B, leading to neuroinflammation, and demonstrates that ASO treatment can reverse this effect in GRN-deficient cells.

bioRxiv · Oct 13, 2026 · PreprintNeuroscience