Structural basis of endogenous lipid recognition and G protein selectivity in GPR119
Dong‐Gyun Kim, Mohsen Ranjbar, Aleksey Raskovalov, Penghao Song, Jayden Salve, Vsevolod Katritch, Vadim Cherezov
The paper presents cryo-EM structures of GPR119 bound to OEA and G proteins, revealing structural basis for G protein selectivity and lipid recognition.
bioRxiv · Aug 28, 2026 · PreprintMolecular Biology