BiochemistrybioRxivPreprint
Structure-based discovery of new GPR119 ligands from on-demand tera-scale chemical space
M. V. T. Nguyen, Dongguyn Kim, Aleksey Raskovalov…·Vsevolod Katritch
This study identifies new GPR119 agonists and antagonists by screening a tera-scale chemical space using structure-based methods and validates them with cryo-EM structures.
DOI 10.64898/2026.11.08.765217